A clinical guide to GLP-1 side effects — what's common, what's rare, what's serious, how long they last, and what you can do to make them manageable. Most people who start semaglutide or tirzepatide injections experience at least one side effect in the first month. The good news is that the vast majority are mild, predictable, and temporary — and once you understand the pattern, most are very manageable. This guide walks through exactly what to expect, when to expect it, and what to do about ea...

A clinical comparison of semaglutide and tirzepatide — including the SURMOUNT-5 head-to-head trial, how they work, effectiveness, side effects, cardiovascular benefits, cost, and which one might be right for you. Semaglutide and tirzepatide are the two most effective weight loss medications currently available — and for most people starting GLP-1 therapy, the choice between them is often the single biggest decision in their treatment plan. Both can be injected once a week. Both reduce appetite....